•    Session 1   
•    Session 2   

• Session 1 • Cell Communication, Metabolism, Signalling and Trafficking

  Chairs: Simona Polo, Annamaria Porcelli

  9:00-10:45

  Raffaella Bonavita, Naples, Italy
  Evidence of an unprecedented cytoplasmic function of DDX11, the Warsaw breakage syndrome DNA helicase, in regulating autophagy

  Giuseppe Fiume, Catanzaro, Italy
  FABP5 is a key player in metabolic modulation and NF-κB dependent inflammation driving pleural mesothelioma

  Alessia Calcagnì, Naples, Italy
  A multi-focal Birt-Hogg-Dubé (BHD) mouse model to study kidney cystogenesis and tumorigenesis pathways

  Virginia Campani, Modena, Italy
  NF-YA splicing triggers a vicious crosstalk between CRC cells and stromal cells within the tumor microenvironment

  Saverio Marchi, Ancona, Italy
  Exploring the interplay between lipid droplets and mitochondria in cancer progression

  10:45-11:15	Coffee break
  11:15-13:00

  Margherita Caputo, Milan, Italy
  Role of RNA and RNA-binding proteins in EGFR endocytosis

  Sara Francesca Colombo, Milan, Italy
  The ER-to-Golgi transport in neuronal cells: the impact of COPII molecular diversity on synapse development and function

  Maria Giovanna De Leo, Lausanne, Switzerland
  CROP2, a Retriever-PROPPIN complex mediating protein export from endosomes to the plasma membrane

  Francesco Consolato, Milan, Italy
  A high-content screening approach to unveil the molecular mechanism of the ciliary response to glutamine

  Marialaura Petroni, Rome, Italy
  Loss of NBS1 disrupts Sonic Hedgehog signaling by impairing the actin cytoskeleton-primary cilium axis

• Session 2 • Cellular stress, Stem cells, Development and Regeneration

  Chairs: Nicoletta Guaragnella, Gabriella Minchiotti

  9:00-10:45

  Veronica Addabbo, Bari, Italy
  Phenotypic rescue in neural progenitors derived from iPSCs of patients with AGC1 deficiency

  Alessandro Bertero, Turin, Italy
  Single cell transcriptional perturbome in pluripotent stem cell models

  Andrea Conte, Naples, Italy
  A multi-omics approach to elucidate the role of synaptojanin 1 (SYNJ1) in health and disease

  Silvia Brunelli, Monza, Italy
  Decoding the inflammatory microenvironment in fibrodysplasia ossificans progressiva: single-cell analysis identifies SPP1+ macrophages as drivers of aberrant FAP differentiation

  Mario Chiariello, Siena, Italy
  MAPK15 controls intracellular lipid uptake and protects mammalian liver from steatotic disease

  10:45-11:15	Coffee break
  11:15-13:00

  Elvira Parrotta, Catanzaro, Italy
  VLMC-mediated extracellular matrix remodeling triggers neurodegneration in sporadic PSP-RS via TGF-β and PI3K/AKT signaling

  Francesco Nicassio, Milan, Italy
  Dissecting the epigenetic and transcriptional programs governing cancer stem cells through single-cell multi-omics and long-read transcriptomics

  Caterina Peggion, Padua, Italy
  Exploring the role of microRNAs and secreted metabolites in myogenesis and amyotrophic lateral sclerosis pathogenesis

  Giuseppe Lupo, Rome, Italy
  The transcription factor Nr2f1 regulates adult neural stem cell quiescence and activation

  Elena Taverna, Milan, Italy
  Intracellular architecture and cell fate choice in the developing brain

Poster presenters are required to be available for discussion during their assigned session. Odd-numbered posters are pesented in the first session while even-numbered ones during the second session.

All posters should stay up for the entire duration of the meeting, independently of the session to which they have been assigned. You are kindly invited to put up your poster upon arrival, from Thursday at 15:00 onwards, and in time for the first poster session. Posters should be taken down before 18:00 on Friday, 26 September.

When preparing your poster please remember that the poster's maximum size is A0 (841 x 1189 mm; width x height).

Correct format...      Wrong format...

•    D A Y   1   
•    D A Y   2   

• Poster Session 1 • 24 September • 18:45-20:45

  P.A1 • Ilenia Agliarulo • Naples
  Intra-Golgi positioning of enzymes: a balancing act between forward and retrograde transport machinery

  P.A3 • Samuele Amadori • Padova
  Targeting mitochondrial calcium by RNA-based therapy in inflammatory bowel diseases

  P.A5 • Matteo Balestra • Milan
  Endocytic landscapes: how context influences endocytosis in physiology and cancer

  P.A7 • Concetta Bianco • Pozzuoli, NA
  The role of the MOSPD proteins in ER-mediated contact sites

  P.A9 • Carlo Cosimo Campa • Turin
  RabAnalyser: a computational framework to explore the cell-to-cell variability of Rab GTPases organization

  P.A11 • Francesca Carriero • Pozzuoli, NA
  Dissecting non–cell-autonomous mechanisms in birt–hogg–dubé (BHD) syndrome to identify novel renal cancer biomarkers.

  P.A13 • Laura Cavazzuti • Rome
  SCD1 mediated lipid desaturation drives radiotherapy resistance in prostate cancer

  P.A15 • Michele Cillo • Pozzuoli, NA
  Selective endoplasmic reticulum immunoprecipitation (ER-Ip) allows in-depth study of ER dynamics

  P.A17 • Alexia Conte • Milan
  Quantitative modelling of EGFR signaling and endocytic fate

  P.A19 • Francesca Corsi • Rome
  Resolving therapy-induced inflammatory eicosanoid storm to prevent prostate cancer chemoresistance

  P.A21 • Nicole Crestan • Aviano, PN
  Role of p27^kip1 in CDK4/6 inhibitor-induced senescence in breast cancer

  P.A23 • Massimo D'Agostino • Naples
  A light-resuming strategy as a new screening method for Sec61 inhibitors: discovery of small molecules down-modulating PD-L1 expression

  P.A25 • Natalia De Cicco • Naples
  DNA aptamers restores mitochondrial dynamics in a cellular model of Huntington’s disease

  P.A27 • Paola Defilippi • Turin
  p140Cap-mediated control of the WNT pathway in breast cancer

  P.A29 • Mariagrazia Di Gennaro • Caserta
  Unravelling the role of the TGN export machinery for basolateral proteins in Amyloid Precursor Protein (APP) transport and processing

  P.A31 • Rosaria Di Martino • Naples
  Autoregulatory circuit regulating basolateral cargo export from the TGN: role of the orphan receptor GPRC5A in PKD signaling and cell polarity

  P.A33 • Antonia Esposito • Padua
  Investigating the role of gut microbiota in inflammatory bowel disease: the impact of microbiota-derived metabolites on mitochondria (dys)function

  P.A35 • Alison Forrester • Namur, Belgium
  Drugging the Endoplasmic Reticulum exit sites (ERES)

  P.A37 • Chiara Gava • Aviano, PN
  Characterization of a model of radioresistant luminal breast cancer

  P.A39 • Aniello Giacco • Pozzuoli, NA
  Fluoxetine MoA uncovered alterations in the LRRK2-Rab-RABIN8 pathway in Mucopolysaccharidosis type IIIA (MPS-IIIA)

  P.A41 • Paolo Grumati • Pozzuoli, NA
  FAM134B is a master regulator of ER-phagy during myogenesis

  P.A43 • Maria Iavazzo • Pozzuoli, NA
  Starvation promotes ribosome autophagy via ZNF598–SQSTM1 axis

  P.A45 • Ozlem Kartal • Padua
  Targeting MICU2 and PDK4 to counteract skeletal muscle atrophy

  P.A47 • Adriana Limone • Naples
  Targeting RPSA to modulate endosomal trafficking and amyloidogenesis in genetic Alzheimer’s disease

  P.A49 • Chiara Lualdi • Novara
  Lysosomal cathepsin D regulates autophagy and lysosomal biogenesis through the mTOR-TFEB axis

  P.A51 • Sara Magliacane Trotta • Naples
  Cancer-derived exosomal-Alu RNA promotes colorectal cancer progression by inducing epithelial-to-mesenchymal transition through NLRP3 inflammasome activation

  P.A53 • Andrea Roberto Marchetti • Turin
  A newly discovered mTOR-STAT3 pathway regulates calcium release and calcium-mediated apoptosis at the ER in triple negative breast cancer

  P.A55 • Francesco Marocco • Rome
  Negative regulation of miRNA sorting into EVs is mediated by the capacity of RBP PCBP2 to impair the SYNCRIP-dependent miRNA loading

  P.A57 • Fabiola Mascanzoni • Naples
  Golgi unlinking during G2 is necessary for spindle formation and cytokinesis

  P.A59 • Maria Chiara Mattevi • Aviano, PN
  Elucidating the role of AREG in luminal breast cancer arising in young women

  P.A61 • Caterina Miro • Naples
  Leptin enhances the intracellular Thyroid Hormone activation in skeletal muscle to boost energy balance

  P.A63 • Alessandra Murabito • Candiolo, TO
  Proximity Labeling and Synchronization of Secretory Traffic Reveal that TBC1D22B is a RAB1B GTPase-activating Protein that Regulates ER-to-Golgi Transport

  P.A65 • Alessandra Palazzi • Naples
  HIPK2 loss causes TDP-43 cytoplasmic mis-localization in mice and human neuroblastoma cells: a new pathogenetic mechanism of ALS

  P.A67 • Ilaria Piazza • Padua
  The role of testosterone in skeletal muscle mitochondrial calcium signalling

  P.A69 • Martina Quagliata • Padua
  RNA therapeutics to target the mitochondrial calcium uniporter

  P.A71 • Antonio Rea • Pozzuoli, NA
  TEX2 controls mitochondrial dynamics at ER-mitochondria contact sites

  P.A73 • Alessandro Ruocco • Naples
  Dysregulation of endosomal pathway driven by Synj1 overexpression affects neuronal homeostasis

  P.A75 • Stefania Salvatore • Bologna
  Investigating neuromodulation of humoral innate immune response in Drosophila melanogaster

  P.A77 • Miriana Sbrissa • Padua
  Impact of ETC complex I dysfunction on mitochondrial Ca²⁺ homeostasis

  P.A79 • Roberto Schirano • Rome
  Overcoming Neuroblastoma Immune Evasion through targeting of cGAS-STING pathway epigenetic alterations

  P.A81 • Maria Concetta Sergio • Pozzuoli, NA
  The role of ESCRT complex in SARS-CoV-2 infection

  P.A83 • Manuela Sollazzo • Bologna
  SPARC sustains survival and metastatisation of CI-impaired ovarian cancer cells

  P.A85 • Raffaele Strippoli • Rome
  Role of autophagy in the activation of the peritoneal membrane by colorectal cancer-produced extracellular vesicles as a first step of peritoneal metastasis formation

  P.A87 • Roberta Visconti • Naples
  A novel role of KMT5a in autophagy: implications for glioblastoma therapy

  P.A89 • Elena Ziviani • Padua
  Induction of Parkin-independent mitophagy in iNeurons by USP14 inhibition

  P.B1 • Natalia Abate • Naples
  CSTB and TRiC/CCT complex: a potential molecular mechanism driving EPM1 pathogenesis 

  P.B3 • Salma Amin • Milan
  Cellular mechanism associated with SLC35A2-CDG brain malformations

  P.B5 • Eustachio Attico • Modena
  Cell therapy strategies for bilateral limbal stem cell deficiency: oral mucosa transplantation in two patients with long-term follow-up and molecular characterization

  P.B7 • Anna Martina Battaglia • Catanzaro
  Neuro-immune crosstalk orchestrates ferroptosis resistance in oral carcinoma

  P.B9 • Giorgia Lucia Benedetto • Catanzaro
  Caspase Inhibition Rescues PKA-CREB Signaling and Restores Neuronal Function in Sporadic Parkinson’s Disease

  P.B11 • Flavia Biamonte • Catanzaro
  Tobacco exposure and ferroptosis resistance in oral cancer: mechanistic insights from cadmium stress

  P.B13 • Maira Certini • Bari
  Reversing time: OSKM-mediated rejuvenation enhances lifespan and healthspan in Drosophila melanogaster

  P.B15 • Arianna Coppola • Naples
  Long non-coding RNA T-UCstem1 modulates paracrine WNT signaling during gastruloid morphogenesis

  P.B17 • Raffaele Covello • Catanzaro
  iPSC-derived dopaminergic neurons recapitulate TAU accumulation and axonal injury in Sporadic Progressive Supranuclear Palsy

  P.B19 • Emile Danvin • Naples
  Neuro-ectodermal and gastruloid models to dissect Kabuki syndrome

  P.B21 • Filomena Del Piano • Naples
  Lipid nanoparticles for in vivo mRNA delivery and direct cell reprogramming into dopamine neurons

  P.B23 • Rosita Di Palma • Naples
  Generation and characterization of an ex vivo model system of idiopathic pulmonary fibrosis for the screening of RNA-based drugs

  P.B25 • Claudia Esposito • Catanzaro
  Functional and Omics Approaches Uncover Mitochondrial Deficits in iPSC-derived Midbrain Organoids from Sporadic PSP Patients

  P.B27 • Chiara Fogliano • Naples
  Retinal degeneration across developmental stages in zebrafish knock-out for impg2: a morphological and ultrastructural investigation

  P.B29 • Cristiana Galeano • Catanzaro
  Iron-regulated redox imbalance modulates keratinocyte inflammation and differentiation in psoriasis-like conditions

  P.B31 • Lucrezia Gerardi • Rome
  ATM inhibition unlocks PARP inhibitor efficacy in MYCN-amplified neuroblastoma

  P.B33 • Eleonora Grecu • Cagliari
  Streamlined forebrain organoids generation via allometric scaling: a lab-friendly approach

  P.B35 • Maria Roberta Iazzetta • Naples
  Exploring glucocorticoid receptor function in dopaminergic neuron survival using Parkinson’s Disease-derived brain organoids

  P.B37 • Antonella Izzo • Naples
  A doxycycline-inducible iPSC-Cas9 system for allele-specific dosage normalization of Hsa21 genes in trisomic cells

  P.B39 • Marianna Maddaluno • Pozzuoli, NA
  Arylsulfatase L (ARSL) regulates chondroitin sulfate desulfation in the golgi to control skeletal development

  P.B41 • Valentina Massa • Milan
  Targeting p300 to mitigate stress-induced premature senescence in 2D and 3D neuronal models

  P.B43 • Evelyn Mazzarelli • Pieve Emanuele, MI
  Twist1 deletion limits EMT activation and promotes epithelial regeneration during acute intestinal epithelial injury

  P.B45 • Giuseppe Natali • Catanzaro
  Role of CD44 in iron-dependent cytotoxicity in HEY and SKOV3 ovarian cancer stem cells

  P.B47 • Annalisa Pecoraro • Naples
  β-Carotene suppresses stem-like properties associated with uL3-mediated chemoresistance in colorectal cancer in vitro and in preclinical CAM model

  P.B49 • Martina Polenghi • Milan
  Golgi traffic and brain development in health and disease

  P.B51 • Giulia Quattrini • Monza
  A new mouse model of JMML highlights differential susceptibility of embryonic hematopoietic stem/progenitor cells to the Kras^G12D mutation

  P.B53 • Irene Relvini • Pozzuoli, NA
  Exploiting the N-degron pathway for the treatment of alpha-1 antitrypsin deficiency liver disease

  P.B55 • Francesca Sacchi • Bologna
  Tuning the activity of corticosteroid receptors promotes cardiomyocyte proliferative and regenerative capacity

  P.B57 • Elena Scordato • Milan
  Primary cilia diversity in brain development and evolution: structural and molecular insights

  P.B59 • Claudia Tito • Rome
  Sorcin deficiency impairs lung morphogenesis, alveolarization, and surfactant production in mice

  P.B61 • Giulia Visani • Milan
  Uncovering the subcellular architecture of mRNAs networks in neural stem cells during brain development

  P.C1 • Damiano Abbo • Turin
  Targeting p130Cas scaffold protein to halt pancreatic cancer invasion and sensitize to AKT inhibition 

  P.C3 • Sara Bellardinelli • Rome
  In vivo study of the immunoregulatory role of KCASH2 in physiological and pathological contexts

  P.C5 • Caterina Boncompagni • Ferrara
  Modulating NLRP3 inflammasome as a therapeutic strategy to restrain radiation-induced atherosclerosis

  P.C7 • Francesca De Amicis • Rende
  Evidences of IL20RA blockade by ritonavir in triple negative breast cancer cells

  P.C9 • Simone Di Paola • Naples
  A role for PARP16 in the regulation of osteosarcoma cell proliferation and survival

  P.C11 • Alessandro Fatica • Rome
  The tRNA-modifying enzyme QTGAL maintains translational fidelity to support breast cancer cell proliferation and migration

  P.C13 • Aurelia Fraticelli • Rome
  Selection and validation of aptamers targeting pancreatic cancer

  P.C15 • Roberto Giambruno • Palermo
  Decoding the RNA and protein interactomes of human pseudouridine synthase 7 (PUS7) via proximity labeling and nanopore sequencing (PLANS)

  P.C17 • Olimpia Iacolare • Naples
  The focal adhesions play a crucial role in the pharyngeal apparatus morphogenesis

  P.C19 • Angela Iuzzolino • Rome
  Transcriptomic and proteomic analyses reveal ATAT1-dependent molecular pathways in lung cancer cells

  P.C21 • Martina Lupoli • Rome
  AntiSense Oligonucleotides (ASO) based treatment in ALS mouse models

  P.C23 • Sandro Montefusco • Pozzuoli, NA
  Combining phenotypic high-content imaging with the repurposing of drugs to tackle lysosomal storage disorders

  P.C25 • Shirin Navacci • Rome
  AMBRA1 controls the Sonic Hedgehog signaling pathway and SHH-medulloblastoma

  P.C27 • Andrea Pelliccia • Rome
  Androgen deprivation induces a reversible quasi-apoptotic state in hormone-sensitive prostate cancer cells, revealing novel therapeutic vulnerabilities

  P.C29 • Roberta Rubino • Turin
  Localized phosphatidylinositol delivery at the intercellular bridge drives cytokinesis completion and prevents aneuploidy in breast cancer

  P.C31 • Gloria Terriaca • Rome
  KCASH2 deficiency enhances DSS‑induced inflammation and tumorigenesis in a colorectal cancer mouse model

  P.C33 • Kristin Tkalčec • Naples
  Toward precision diagnostics: aptamer-gold nanoparticle biosensing for detection of breast cancer

• Poster Session 2 • 25 September • 19:15-21:00

  P.A2 • Aya Al Saidi • Padova
  Elucidating the role of MCU in melanogenesis

  P.A4 • Fabrizia Ametrano • Naples
  Modeling fructose-induced brain alterations:integrating in vivo and stem cell-based in vitro systems

  P.A6 • Sabrina Battista • Naples
  The HMGA1/NUMB axis as a metabolic vulnerability to improve PI3K inhibitors efficacy in cancer therapy

  P.A8 • Mariarita Brancaccio • Naples
  Uncovering a New Regulatory Pathway in IPF: The Role of miR-143-3p and AGR2 in Fibrotic Progression

  P.A10 • Carolina Cané • Naples
  HIPK2 inhibition promotes cytoplasmic accumulation of TDP-43 and its interaction with VAPB: a proteomic insight into ALS pathogenesis

  P.A12 • Elisa Cataudella • Pavia
  A transiently amplifying and self-limiting Nova2-ADAR2 circuit in endothelial cells

  P.A14 • Raffaella Ciancio • Naples
  Sigma-1R: a key modulator of Ca²⁺ homeostasis and inter-organelle communication in ALS

  P.A16 • Vittorio Cirillo • Baronissi, SA
  Lipid editing at the Endoplasmic Reticulum: SYNJ1 maintains PI(4)P homeostasis for COPII-driven export

  P.A18 • Paola Cordella • Lecce
  Role of peripherin in lysosomal degradation activity and autophagy

  P.A20 • Katia Cortese • Genoa
  Organelle triads as emergent signaling platforms in HER2+ breast cancer cells under trastuzumab–deruxtecan treatment

  P.A22 • Valeria Crippa • Milan
  The role of tetraspanins in extracellular vesicle-mediated clearance of insoluble TDP-43

  P.A24 • Elena D'Apolito • Naples
  Siah2-associated mitochondrial dysfunction in experimental models of Parkinson’s Disease

  P.A26 • Maria Chiara De Santis • Turin
  Glutamine sensing in pancreatic cancer

  P.A28 • Gennaro Di Bonito • Pozzuoli, NA
  FGF signaling promotes lysosome biogenesis in chondrocytes via the Mannose Phosphate Receptor pathway

  P.A30 • Chiara Di Malta • Pozzuoli, NA
  GPNMB activates lysosomal exocytosis via VAMP7 to coordinate pigmentation, cellular clearance and invasion

  P.A32 • Alberico Di Pinto • Rome
  The lysosomal acid phosphatase 2 (ACP2) targets ERAP1 for ER-to-lysosome-associated degradation and suppresses Sonic Hedgehog medulloblastoma growth

  P.A34 • Alessandra Ferraresi • Novara
  P53-mediated autophagy degradation of NKX3-2 improves ovarian cancer prognosis

  P.A36 • Raffaella Gallo • Catanzaro
  DYRK3 regulates the material properties of Endoplasmi Reticulum Exit Sites and is required for anterograde trafficking

  P.A38 • Noemi Ghiglione • Turin
  MLK4 regulates mitochondrial dynamics and metabolic rewiring in pancreatic cancer

  P.A42 • Alessandro Guarnieri • Padua
  Mitochondrial Ca²⁺ uniporter modulation in models of liver inflammation

  P.A44 • Natalia Iseppato • Modena
  NF-YA-induced metabolic reprogramming in CRC cells promotes M2 macrophage polarization to establish an immunosuppressive microenvironment

  P.A46 • Gianmaria Leone • Naples
  Dissecting and piloting the intracellular trafficking of adeno-associated viruses (AAVs)

  P.A48 • Mattia Longanesi • Bologna
  Functional and structural analysis of TnBVANK1 a bracovirus IκB-like protein

  P.A50 • Martina Maffezzoni • Brescia
  Profiling of miR-98-5p, miR-130a-3p, and miR-1246 levels in tissue and liquid biopsies of patients with hepatocellular carcinoma

  P.A52 • Vanessa Mancini • Rome
  Contribution of the cation channel TRPA1 in the targeting of FGFR2c to the lipid raft signaling platforms in pancreatic ductal adenocarcinoma cells

  P.A54 • Irene Mariani • Rome
  Unrevealing the interactome of ALK2 receptor in hypoxic condition: relevance for Fibrodysplasia ossificans progressiva (FOP) and Diffuse intrinsic pontine glioma (DIPG) diseases

  P.A56 • Simone Mas • Palermo
  A mechanobiological approach to study PDAC progression and pharmacological response

  P.A58 • Francesco Massaro • Pozzuoli, NA
  Dissecting the clinical variability observed in HNF1B associated phenotypes

  P.A60 • Carmen Miano • Bologna
  Prolonged stimulation with high doses of EGF reduces breast cancer cell aggressiveness by reducing ERBB2 stability

  P.A62 • Concetta Mosca • Naples
  Identification of a novel role of GLUT2 in adeno-associated virus trafficking

  P.A64 • Pampa Pain • Padova
  Beyond Respiration: mitochondrial calcium uptake as therapeutic target in lung inflammation

  P.A66 • Raffaella Petruzzelli • Pozzuoli, NA
  Oncogenic Consequences of Golgi Copper Dysregulation: ATP7B Loss Links Wilson Disease to Immune Evasion and Cholangiocarcinoma

  P.A68 • Antonello Prodomo • Pozzuoli, NA
  Role of endosome composition in NLRP3 activation

  P.A70 • Luca Quattrocchi • Rome
  RNA-binding proteins role in extracellular vesicles mediated cellular communication

  P.A72 • Simona Ricciardi • Pozzuoli, NA
  The Role of Atlastin in the coupling of Replication and Assembly of SARS CoV-2

  P.A74 • Paola Rusmini • Milan
  Lysosome exocytosis and neurite outgrowth: new insights into trehalose mechanism of action

  P.A76 • Irene Sambri • Pozzuoli, NA
  Modeling tubulopathy and cardiomyopathy syndromes driven by RRAGD mutations

  P.A78 • Irene Schiano Lomoriello • Milan
  The endocytic protein EPN3: a new prognostic marker and potential therapeutic target in metastatic breast cancer

  P.A80 • Simona Ida Scorza • Bari
  From flow to function: fluid shear stress orchestrates autophagy and AQP2 trafficking in collecting duct cells

  P.A82 • Angela Serpico • Naples
  Inhibitory control of Cdk1 licenses mitosis exit

  P.A86 • Alessandra Tavoni • Pavia
  Mitostitch: a new tool to investigate the structural and functional components of mitochondrial-nuclear communication

  P.A88 • Ping Zhang • Turin
  SH3BP5L triggers RAB11A/KIF5B association and promotes ITGB1 recycling in triple-negative breast cancer metastasis

  P.B2 • Sadra Afra • Naples
  A protocol to identify paternal lipids transferred from sperm to oocyte during fertilization using stable isotope in-vivo labeling and single embryo mass-spectrometry 

  P.B4 • Filomena Amoroso • Naples
  Decoding epigenetic control of 3D gastruloids through Epi-Drug screening

  P.B6 • Ilaria Aurigemma • Fisciano, SA
  Significant improvement of cardiac outflow tract septation defects in a DiGeorge syndrome model after minoxidil treatment

  P.B8 • Claudia Bellomo • NAPOLINaples
  Intestinal Organoid as a model of celiac disease and its comorbidities

  P.B10 • Jessika Bertacchini • Modena
  Polyglutamine expansion of androgen receptor induces skeletal abnormalities during bone development in a mouse model of spinal and bulbar muscular atrophy

  P.B12 • Chiara Bongiovanni • Bologna
  BMPs and cardiomyocyte regeneration: insights into postnatal heart repair

  P.B14 • Michela Coiro • Rome
  Uncovering the role of circHIPK3 in cellular stress adaptation in TNBC

  P.B16 • Angelita Costantino • Alicante, Spain
  The CCR8/CCL8 axis promotes breast cancer lung metastases in mice

  P.B18 • Emanuele Cricchi • Udine
  The role of class IIa HDACs in the epigenetic control of leiomyosarcomas

  P.B20 • Greta Deidda Tarquini • Rome
  Cerium oxide nanoparticles as novel UV-protective agents with stable antioxidant properties to prevent skin cancer development and progression

  P.B22 • Simona Di Marino • Naples
  Combined activity of nicotine and caffeine in the amphibian model Xenopus laevis

  P.B24 • Moises Di sante • Pavia
  Calipers: a method for cell cycle-aware live imaging in phenotyping and regeneration studies

  P.B26 • Emanuele Ferrario • Vercelli
  AKRs confer oligodendrocytes resistance to differentiation-stimulated ferroptosis

  P.B28 • Salvatore Gagliotta • Naples
  The role of TFEB in kidney pathogenesis in Tuberous Sclerosis Complex: insights from human kidney organoids

  P.B30 • Gilda Gargiulo • Naples
  Generation and characterization of lung organoids from human pluripotent stem cells to tackle lung fibrosis

  P.B32 • Giorgia Ghirardo • Padua
  Role of mitochondrial calcium in the activation and differentiation of muscle stem cells during skeletal muscle regeneration

  P.B34 • Ombretta Guardiola • Naples
  Exploring the role of the chemokine receptor CXCR2 in muscle stem cell heterogeneity

  P.B36 • Alice Italia • Milan
  Functional impact of Toll-like Receptor 4 (TLR4) modulation in lung fibrosis-associated fibroblasts

  P.B38 • Vincenzo Lullo • Naples
  Modeling and correcting ICF syndrome in iPSCs: DNMT3B and ZBTB24 dysfunction drives haematopoietic imbalance

  P.B40 • Francesco Mangia • Naples
  PARP16 as a key regulator of endoplasmic reticulum stress response: therapeutic implications in osteosarcoma

  P.B42 • Gilla Mazzanti • Rome
  New strategies to improve the response of acute myeloid leukemia cells to targeted therapies by overcoming the protective effect of the bone marrow mesenchymal stem cells

  P.B44 • Maria Elena Miranda Banos • Rome
  Neuronal toxicity of mutant neuroserpin underlying neurodegeneration FENIB

  P.B46 • Chiara Parodi • Milan
  Modelling Cornelia de Lange syndrome: unravelling the role of the Tdark gene MAU2

  P.B48 • Michela Pecoraro • Salerno
  Er stress response is influenced by relationship between UPR and mitochondria

  P.B50 • Sabrina Quaresima • Rome
  Neurogenesis-astrogliogenesis balance: the role of Tsukushi during mouse neocortical development

  P.B52 • Maria Chiara Rainone • Milano
  Role of Epsin 3 in mammary gland development, lactation and cancer

  P.B54 • Silvia Ruggiero • Benevento
  Unravelling the role of HDAC11/STAT3/GSDMD pathway in SOD1-G93A skeletal muscle toxicity

  P.B56 • Mohammad Shayan Samavat • Naples
  Evidence of sperm lipids as epigenetic drivers of intergenerational inheritance

  P.B58 • Andrea Tedde • Padua
  Investigating the role of mitochondrial Ca2+ signalling and MiR-486 in RYR1-related core myopathies

  P.B60 • Marta Urbani • Rome
  Therapy-promoted prostate cancer repopulation and acquired cell-resistance (CRAC) implies vulnerability to ferroptosis via lipoxygenase activation

  P.C2 • Ludovica Altieri • Rome
  An unexpected role of α-tubulin N-acetyltransferase 1 (ATAT1) in the regulation of primary cilia 

  P.C4 • Naym Blal • Salerno
  Engineering the ECM to influence macrophage responses: early insights for immunomodulatory applications.

  P.C6 • Rosa Cardone • Bari
  A Gemcitabine-derived prodrug as a more effective approach to GEM in overcoming the tumor microenviroment-induced pancreatic cancer metastatic behavior and chemoresistance

  P.C8 • Mario De Gregorio • Turin
  From spine organization to synaptic functionality: dissecting the role of SKT/KIAA1217, an emerging scaffold in the postsynaptic complex

  P.C10 • Emanuele Fantastico • Turin
  PIP5K1A-mediated regulation of PIP₂ is essential for proper metaphase spindle assembly and accurate mitotic progression.

  P.C12 • Margherita Ferretti • Rome
  Shared immune evasion mechanisms in endometrial cancer and recurrent miscarriage: insights from the maternal–fetal interface

  P.C14 • Giorgia Gemma • Naples
  Dissecting the Role of TRIM8 in Focal Segmental Glomerulosclerosis and Neurodevelopmental Syndrome

  P.C16 • Francesca Giulimondi • Rome
  Apolipoprotein-enriched nucleoproteic corona improves effective gene delivery in brain cancer models

  P.C18 • Roberta Iannitti • Naples
  MKK7 is implicated in JNK2 activation and Golgi unlinking

  P.C20 • Ludovica Lospinoso Severini • Rome
  Arsenic trioxide improves the sensitivity to immunotherapy in non-small cell lung cancer

  P.C22 • Celeste Milani • Padova
  SPLIDS: a novel splitGFP based delivery sensor for monitoring RNA delivery and translation efficiency

  P.C24 • Maria Chiara Mottola • Pavia
  Characterization of the LINP1/LINC00707 locus in a LigI-defective model of chronic DNA damage

  P.C26 • Sabela Nikolli • Rome
  Dysregulation of microRNA biogenesis in cancer: the impact of mutant p53/Dicer complex

  P.C28 • Marianna Roca • Fisciano, SA
  Cellular behavior in response to nanomaterials: the role of the microenvironment in modulating macrophage response to polystyrene nanoparticles

  P.C30 • Gaia Sarcinelli • Pieve Emanuele, MI
  Functional contribution of Epithelial-to-Mesenchymal Transition in cancer initiation

  P.C32 • Marialuisa Testa • Pozzuoli, NA
  Kidney organoids as platform for investigating monogenic diseases and AAV gene therapy approaches

  P.C34 • Veronica Vitto • Ferrara
  BAP1 safeguards against mesothelioma by stabilizing VDAC3 and preserving mitochondrial integrity